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Score-based diffusion models for diffuse optical tomography with uncertainty quantification

Schneider, Fabian, Mozumder, Meghdoot, Tamarov, Konstantin, Taghizadeh, Leila, Tarvainen, Tanja, Helin, Tapio, Duong, Duc-Lam

arXiv.org Machine Learning

Score-based diffusion models are a recently developed framework for posterior sampling in Bayesian inverse problems with a state-of-the-art performance for severely ill-posed problems by leveraging a powerful prior distribution learned from empirical data. Despite generating significant interest especially in the machine-learning community, a thorough study of realistic inverse problems in the presence of modelling error and utilization of physical measurement data is still outstanding. In this work, the framework of unconditional representation for the conditional score function (UCoS) is evaluated for linearized difference imaging in diffuse optical tomography (DOT). DOT uses boundary measurements of near-infrared light to estimate the spatial distribution of absorption and scattering parameters in biological tissues. The problem is highly ill-posed and thus sensitive to noise and modelling errors. We introduce a novel regularization approach that prevents overfitting of the score function by constructing a mixed score composed of a learned and a model-based component. Validation of this approach is done using both simulated and experimental measurement data. The experiments demonstrate that a data-driven prior distribution results in posterior samples with low variance, compared to classical model-based estimation, and centred around the ground truth, even in the context of a highly ill-posed problem and in the presence of modelling errors.



Lived Experience in Dialogue: Co-designing Personalization in Large Language Models to Support Youth Mental Well-being

Guan, Kathleen W., Giri, Sarthak, Amara, Mohammed, Jansen, Bernard J., Liscio, Enrico, Esherick, Milena, Owayyed, Mohammed Al, Ratkute, Ausrine, Sedrakyan, Gayane, de Reuver, Mark, Goncalves, Joao Fernando Ferreira, Figueroa, Caroline A.

arXiv.org Artificial Intelligence

We conducted three 90 - minute workshops at Talenthub Op Zuid, each with a different group of participants (total N=24, MAge =17.6, SD=1.2, see S upplement for additional details). In the first workshop, participants reviewed the prior 13 personas from Stage 1 and critiqued them for gaps in relevance. The scoping personas generated from survey and forum data gave youth stakeholders a concrete starting point for consulting as experts by experience in initial co - design activities. They challenged the realism of the scoping personas . Using fill - in - the - blank templates to guide but not restrict their persona creation (created by a youth member of the research team with design training, see Supplement), youth added contextual details to the project personas, such as daily routines, stressors, and digital habits, and brainstormed plausible backstories involving bullying, school difficulties, or parental conflict. The second workshop engaged a new participant group who expanded on previous outputs and addressed additional questions on living environment and emotional support needs, as this was suggested as relevant by youth from the prior workshop . Participants revised or created new personas b ased on their own or peers' experiences. In t he third workshop, a new group of participants again reviewed prior co - creation and outputs and further refined the personas .


Dexterous Robotic Piano Playing at Scale

Chen, Le, Zhao, Yi, Schneider, Jan, Gao, Quankai, Guist, Simon, Qian, Cheng, Kannala, Juho, Schölkopf, Bernhard, Pajarinen, Joni, Büchler, Dieter

arXiv.org Artificial Intelligence

This work has been submitted to the IEEE for possible publication. Abstract--Endowing robot hands with human-level dexterity has been a long-standing goal in robotics. Bimanual robotic piano playing represents a particularly challenging task: it is high-dimensional, contact-rich, and requires fast, precise control. Our approach is built on three core components. First, we introduce an automatic fingering strategy based on Optimal Transport (OT), allowing the agent to autonomously discover efficient piano-playing strategies from scratch without demonstrations. Second, we conduct large-scale Reinforcement Learning (RL) by training more than 2,000 agents, each specialized in distinct music pieces, and aggregate their experience into a dataset named RP1M++, consisting of over one million trajectories for robotic piano playing. Extensive experiments and ablation studies highlight the effectiveness and scalability of our approach, advancing dexterous robotic piano playing at scale. Achieving human-level dexterity remains one of the central challenges in robotics. The difficulty stems from the breadth of challenges ranging from contact-rich manipulation to dynamic athletic tasks, each posing distinct demands. Manipulation tasks, such as grasping or reorienting objects [1], require sustained application of appropriate forces at moderate speeds across objects with diverse shapes, materials, and weight distributions. Dynamic tasks, such as juggling [2] or table tennis [3], involve frequent contact changes, demand high precision, and allow little tolerance for error due to the rarity of contact opportunities. The combination of requiring both precision and speed makes reproducing human-level dexterity particularly challenging. Q. Gao is with the University of Southern California, CA 90007, United States (e-mail: quankaig@usc.edu). Q. Cheng is with Imperial College London, SW7 2AZ, London, United Kingdom (e-mail: c.qian24@imperial.ac.uk). J. Kannala is with the University of Oulu, 90570 Oulu, Finland. D. B uchler is also with the University of Alberta (Canada), the Alberta Machine Intelligence Institute (Amii), & holds a Canada CIFAR AI Chair.


GEPOC Parameters -- Open Source Parametrisation and Validation for Austria, Version 2.0

Bicher, Martin, Viehauser, Maximilian, Giannandrea, Daniele, Kastinger, Hannah, Brunmeir, Dominik, Rippinger, Claire, Urach, Christoph, Popper, Niki

arXiv.org Artificial Intelligence

GEPOC, short for Generic Population Concept, is a collection of models and methods for analysing population-level research questions. For the valid application of the models for a specific country or region, stable and reproducible data processes are necessary, which provide valid and ready-to-use model parameters. This work contains a complete description of the data-processing methods for computation of model parameters for Austria, based exclusively on freely and publicly accessible data. In addition to the description of the source data used, this includes all algorithms used for aggregation, disaggregation, fusion, cleansing or scaling of the data, as well as a description of the resulting parameter files. The document places particular emphasis on the computation of parameters for the most important GEPOC model, GEPOC ABM, a continuous-time agent-based population model. An extensive validation study using this particular model was made and is presented at the end of this work.